Staff employed at University of Copenhagen – University of Copenhagen

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  1. Published

    Structure/activity Relationship of Thapsigargin Inhibition on the Purified Golgi/secretory Pathway Ca2+/Mn2+ Transport ATPase (SPCA1a). / Jialin, Chen; de Raeymaecker, Joren ; Hovgaard, Jannik Brøndsted; Smaardijk, Susanne; Vandecaetsbeek, Ilse; Wuytack, Frank; Møller, Jesper Vuust; Eggermont, Jan; de Meyer, Marc; Christensen, Søren Brøgger; Vangheluwe, Peter.

    In: Journal of Biological Chemistry, Vol. 292, No. 17, M117.778431, 06.03.2017, p. 6938-6951.

    Publication: Research - peer-reviewJournal article

  2. Published

    Basic characteristics and kinetics of degradation in aqueous buffer of selected diclofenac prodrugs intended for joint injection. / Mertz, Nina; Larsen, Susan Weng; Larsen, Claus Selch.

    2016. Poster session presented at 10th World Meeting on Pharmaceutics, Biopharmaceutics and Pharmaceutical Technology, Glasgow, United Kingdom.

    Publication: Research - peer-reviewPoster

  3. Published

    The potential of protein-nanomaterial interaction for advanced drug delivery. / Peng, Qiang; Mu, Huiling.

    In: Journal of Controlled Release, Vol. 225, 23.01.2016, p. 121-132.

    Publication: Research - peer-reviewJournal article

  4. Published

    Cytochrome P450 Mediated Drug Metabolism. / Olsen, Lars; Jørgensen, Flemming Steen; Oostenbrink, Chris.

    New Horizons in Predictive Drug Metabolism and Pharmacokinetics. ed. / Alan G.E. Wilson. Cambridge : Royal Society of Chemistry, 2016. p. 66-78 (RSC Drug Discovery, Vol. 49).

    Publication: Research - peer-reviewBook chapter

  5. Published

    Iminolactones as Tools for Inversion of the Absolute Configuration of alpha-Amino Acids and as Inhibitors of Cancer Cell Proliferation. / Jensen, Christina Mernøe; Chow, Hsiao-Qing; Chen, Ming; Zhai, Lin; Frydenvang, Karla Andrea; Liu, Huizhen ; Franzyk, Henrik; Christensen, Søren Brøgger.

    In: European Journal of Medicinal Chemistry, Vol. 114, 2016, p. 118-133.

    Publication: Research - peer-reviewJournal article

  6. Published

    Thapsigargin, origin, chemistry, structure-activity relationships and prodrug development. / Doan, Thi Quynh Nhu; Christensen, Søren Brøgger.

    In: Current Pharmaceutical Design, Vol. 21, No. 38, 10.2015, p. 5505-5517.

    Publication: Research - peer-reviewReview

  7. Published

    Selecting key toxins for focused development of elapid snake antivenoms and inhibitors guided by a Toxicity Score. / Laustsen, Andreas Hougaard; Lohse, Brian.

    In: Toxicon, Vol. 104, 15.09.2015, p. 43-45.

    Publication: Research - peer-reviewLetter

  8. Published

    Kolliphor surfactants affect solubilization and bioavailability of fenofibrate. Studies of in vitro digestion and absorption in rats. / Berthelsen, Ragna; Holm, Rene; Jacobsen, Jette; Kristensen, Jakob; Abrahamsson, Bertil; Müllertz, Anette.

    In: Molecular Pharmaceutics, Vol. 12, No. 4, 06.04.2015, p. 1062-1071.

    Publication: Research - peer-reviewJournal article

  9. Published

    Noter til Organisk Kemi for Biovidenskab : Organisk og bioorganisk kemi 2015. / Nielsen, John.

    2015, 25 p. .

    Publication: EducationOther contribution

  10. Published

    Investigations and design of pyridine-2-carboxylic acid thiazol-2-ylamide analogs as methionine aminopeptidase inhibitors using 3D-QSAR and molecular docking. / Hauser, Alexander Sebastian.

    In: Medicinal Chemistry Research, Vol. 23, No. 8, 01.08.2014, p. 3861.

    Publication: Research - peer-reviewJournal article

  11. Published
  12. Published

    Organ culture of C57BL/6 mouse arteries with LPS as an in vitro model of vascular inflammation. / Outzen, Emilie Middelbo; Mehryar, Rahila; Boonen, Harrie C.M.; Nielsen, Anette Sams; Sheykhzade, Majid.

    2013. Poster session presented at DRA Summer School 2013, Copenhagen, Denmark.

    Publication: ResearchPoster

  13. Published

    Pattern-oriented Agent-based Monte Carlo simulation of Cellular Redox Environment. / Tang, Jiaowei; Holcombe, Mike ; Boonen, Harrie C.M.

    2013. Poster session presented at DRA Summer School 2013, Copenhagen, Denmark.

    Publication: ResearchPoster

  14. Published

    Prolonged naproxen joint residence time after intra-articular injection of lipophilic solutions comprising a naproxen glycolamide ester prodrug in the rat. / Thing, Mette; Lu, Yi; Agårdh, Li; Larsen, Claus Selch; Ostergaard, Jesper; He, Wei; Wu, Wei; Larsen, Frank; Larsen, Susan Weng.

    In: International Journal of Pharmaceutics, Vol. 451, No. 1-2, 15.07.2013, p. 34-40.

    Publication: Research - peer-reviewJournal article

  15. Liposomal temocene (m-THPPo) photodynamic treatment induces cell death by mitochondria-independent apoptosis. / Soriano, Jorge; Garcia-Diaz, Maria; Mora, Margarita; Sagristá, Maria Lluïsa; Nonell, Santi; Villanueva, Angeles; Stockert, Juan Carlos; Cañete, Magdalena.

    In: Biochimica et Biophysica Acta, Vol. 1830, No. 10, 28.05.2013, p. 4611-4620.

    Publication: Research - peer-reviewJournal article

  16. Published

    Development and validation of an SPE methodology combined with LC-MS/MS for the determination of four ionophores in aqueous environmental matrices. / Bak, Søren Alex; Hansen, Martin; Krogh, Kristine Andersen; Brandt, Asbjørn; Halling-Sørensen, Bent; Björklund, Erland.

    In: International Journal of Environmental Analytical Chemistry, Vol. 93, No. 14, 25.02.2013, p. 1500-1512.

    Publication: Research - peer-reviewJournal article

  17. Published

    Altered anziety/depression-like behaviours in mice deficient in tetrahydrobiopterin. / Nasser, Arafat; Birk Møller, Lisbeth; Andreasen T., Jesper.


    Publication: Research - peer-reviewConference abstract for conference

  18. Exploring the solid-form landscape of pharmaceutical hydrates : transformation pathways of the sodium naproxen anhydrate-hydrate system. / Raijada, Dharaben Kaushikkumar; Bond, Andrew; Larsen, Flemming Hofmann; Cornett, Claus; Qu, Haiyan; Rantanen, Jukka.

    In: Pharmaceutical Research, Vol. 30, No. 1, 01.2013, p. 280-289.

    Publication: Research - peer-reviewJournal article

  19. Published

    Exploring the solid-form landscape of pharmaceutical hydrates : transformation pathways of the sodium naproxen anhydrate-hydrate system. / Raijada, Dharaben Kaushikkumar; Bond, Andrew; Larsen, Flemming Hofmann; Cornett, Claus; Qu, Haiyan; Rantanen, Jukka.

    In: Pharmaceutical Research, Vol. 30, No. 1, 2013, p. 280-289.

    Publication: Research - peer-reviewJournal article

  20. Published

    Lactate dehydrogenase assay for assessment of polycation cytotoxicity. / Parhamifar, Ladan; Andersen, Helene; Moghimi, Seyed Moien.

    Nanotechnology for Nucleic Acid Delivery. Vol. 948 2013. p. 13-22 (Methods in Molecular Biology).

    Publication: ResearchBook chapter

  21. Published

    Pollution Pathways of Pharmaceutical Residues in the Aquatic Environment on the Island of Mallorca, Spain. / Rodríguez-Navas, Carlos ; Björklund, Erland; Bak, Søren Alex; Hansen, Martin; Krogh, Kristine Andersen; Maya, Fernando; Forteza, Rafael; Cerdà, Víctor.

    In: Archives of Environmental Contamination and Toxicology, Vol. 61, No. 1, 2013, p. 56-66.

    Publication: Research - peer-reviewJournal article

  22. Published

    Strategic funding priorities in the pharmaceutical sciences allied to Quality by Design (QbD) and Process Analytical Technology (PAT). / Aksu, Buket; De Beer, Thomas; Folestad, Staffan; Ketolainen, Jarkko; Lindén, Hans; Lopes, Joao Almeida; de Matas, Marcel; Oostra, Wim; Rantanen, Jukka; Weimer, Marco.

    In: European Journal of Pharmaceutical Sciences, Vol. 47, No. 2, 29.09.2012, p. 402-405.

    Publication: Research - peer-reviewJournal article

  23. Published

    Quality assessment of Tulbaghia rhizomes. / Jäger, Anna; Stafford, Gary Ivan.

    In: South African Journal of Botany, Vol. 82, 09.2012, p. 92-98.

    Publication: Research - peer-reviewJournal article

  24. Published

    Solvent-mediated amorphous-to-crystalline transformation of nitrendipine in amorphous particle suspensions containing polymers. / Xia, Dengning; Wu, Jian-Xiong; Cui, Fude; Qu, Haiyan; Rades, Thomas; Rantanen, Jukka; Yang, Mingshi.

    In: European Journal of Pharmaceutical Sciences, Vol. 46, No. 5, 15.08.2012, p. 446-454.

    Publication: Research - peer-reviewJournal article

  25. Published

    Genetic fuzzy system modeling and simulation of vascular behaviour. / Tang, Jiaowei; Boonen, Harrie C.M.

    2012. Poster session presented at Danish Cardiovascular Research Academy 2012 summer meeting at the Sandbjerg Estate , Sønderborg, Denmark.

    Publication: Research - peer-reviewPoster

  26. Published

    Studies of H3K4me3 demethylation by KDM5B/Jarid1B/PLU1 reveals strong substrate recognition in vitro and identifies 2,4-pyridine-dicarboxylic acid as an in vitro and in cell inhibitor. / Kristensen, Line Hyltoft; Nielsen, Anders Laerke; Helgstrand, Charlotte; Lees, Michael; Cloos, Paul; Kastrup, Jette Sandholm; Helin, Kristian; Olsen, Lars; Gajhede, Michael.

    In: F E B S Journal, Vol. 279, No. 11, 06.2012, p. 1905-1914.

    Publication: Research - peer-reviewJournal article

  27. Published

    Chemical composition of the essential oil from Microlicia graveolens growing wild in Minas Gerais. / Toudahl, Anja B; Filho, Sidney A V; Souza, Gustavo H B; Morais, Luisa D; dos Santos, Orlando D H ; Jäger, Anna.

    In: Revista Brasileira de Farmacognosia, Vol. 22, No. 3, 05.2012, p. 680-681.

    Publication: Research - peer-reviewLetter

  28. Published

    Comment on "Binding free energies of inhibitors to iron porphyrin complex as a model for cytochrome P450". / Rydberg, Patrik.

    In: Biopolymers, Vol. 97, No. 4, 04.2012, p. 250-251.

    Publication: Research - peer-reviewComment/debate

  29. Published

    Concise synthesis of new bridged-nicotine analogues. / Crestey, François; Hooyberghs, Geert ; Kristensen, Jesper Langgaard.

    In: Tetrahedron, Vol. 68, No. 5, 04.02.2012, p. 1417-1421.

    Publication: Research - peer-reviewJournal article

  30. Published

    Intersubunit bridge formation governs agonist efficacy at nicotinic acetylcholine alpha4beta2 receptors : Unique role of halogen bonding revealed. / Rohde, Line Aagot Hede; Ahring, Philip Kiær; Jensen, Marianne Lerbech; Nielsen, Elsebet Østergaard; Peters, Dan; Helgstrand, Charlotte; Krintel, Christian; Harpsøe, Kasper; Gajhede, Michael; Kastrup, Jette Sandholm; Balle, Thomas.

    In: The Journal of biological chemistry, Vol. 287, No. 6, 03.02.2012, p. 4248-4259.

    Publication: Research - peer-reviewJournal article

  31. Published

    3-Alkyl- and 3-amido-isothiazoloquinolin-4-ones as ligands for the benzodiazepine site of GABAA receptors. / Nilsson, Jakob; Nielsen, Elsebet Østergaard; Liljefors, Tommy; Nielsen, Mogens Peter Cherly; Sterner, Olov.

    In: Bioorganic Chemistry, Vol. 40, 02.2012, p. 125-130.

    Publication: Research - peer-reviewJournal article

  32. Published

    Biased agonism of the calcium-sensing receptor. / Thomsen, Alex Rojas Bie; Hvidtfeldt, Maja; Bräuner-Osborne, Hans.

    In: Cell Calcium, Vol. 51, No. 2, 02.2012, p. 107-116.

    Publication: Research - peer-reviewJournal article

  33. Published

    Ligand-based site of metabolism prediction for cytochrome P450 2D6. / Rydberg, Patrik; Olsen, Lars.

    In: A C S Medicinal Chemistry Letters, Vol. 3, No. 1, 12.01.2012, p. 69-73.

    Publication: Research - peer-reviewLetter

  34. Published

    (1S, 3S)-3-amino-4-difluoromethylenyl-1-cyclopentanoic acid (CPP-115), a potent gamma-aminobutyric acid aminotransferase inactivator for the treatment of cocaine addiction. / Pan, Yue; Gerasimov, Madina R; Kvist, Trine; Wellendorph, Petrine; Madsen, Karsten Kirkegaard; Pera, Elena; Lee, Hyunbeom; Schousboe, Arne; Chebib, Mary; Bräuner-Osborne, Hans; Craft, Cheryl M; Brodie, Jonathan D; Schiffer, Wynne K; Dewey, Stephen L; Miller, Stephen R; Silverman, Richard B.

    In: Journal of Medicinal Chemistry, Vol. 55, No. 1, 01.01.2012, p. 357-366.

    Publication: Research - peer-reviewJournal article

  35. Published

    Thermodynamics and structural analysis of positive allosteric modulation of the ionotropic glutamate receptor GluA2. / Krintel, Christian; Frydenvang, Karla; Olsen, Lars; Kristensen, Maria T; de Barrios, Oriol; Naur, Peter; Francotte, Pierre; Pirotte, Bernard; Gajhede, Michael; Kastrup, Jette Sandholm.

    In: Biochemical Journal, Vol. 441, No. 1, 01.01.2012, p. 173-178.

    Publication: Research - peer-reviewJournal article

  36. Published

    Evaluation of the antibacterial activity of Chilean plants traditionally used for wound healing therapy against multidrug-resistant Staphylococcus aureus. / Holler, Jes Gitz; Søndergaard, Karen ; Slotved, Hans-Christian; Gúzman, Alfonso; Mølgaard, Per.

    In: Planta Medica, Vol. 78, No. 2, 01.2012, p. 200-205.

    Publication: Research - peer-reviewLetter

  37. Published

    Side-chain interactions form late and cooperatively in the binding reaction between disordered peptides and PDZ domains. / Haq, S Raza; Chi, Celestine N; Bach, Anders; Dogan, Jakob; Engström, Åke; Hultqvist, Greta; Karlsson, O. Andreas; Lundström, Patrik; Montemiglio, Linda Celeste; Strømgaard, Kristian; Gianni, Stefano; Jemth, Per.

    In: American Chemical Society. Journal, Vol. 134, No. 1, 01.2012, p. 599-605.

    Publication: Research - peer-reviewJournal article

  38. Published

    In vitro efficacy testing of praziquantel, ivermectin, and oxfendazole against Taenia Solium cysts. / Cederberg, S.; Sikasunge, C.S.; Andersson, Åsa; Johansen, Maria Vang.

    In: Journal of Parasitology Research, Vol. 2012, 2012.

    Publication: Research - peer-reviewJournal article

  39. Published

    In vitro release from oil injectabels for intra-articular administration : importance of interfacial area, diffusivity and partitioning. / Thing, Mette Agergaard; Larsen, Claus Selch; Østergaard, Jesper; Jensen, Henrik; Larsen, Susan Weng.

    In: European Journal of Pharmaceutical Sciences, Vol. 45, No. 3, 2012, p. 351-357.

    Publication: Research - peer-reviewJournal article

  40. Published

    A 3D-QSAR-driven approach to binding mode and affinity prediction. / Tosco, Paolo; Balle, Thomas.

    In: Journal of Chemical Information and Modeling, Vol. 52, No. 2, 2012, p. 302-307.

    Publication: Research - peer-reviewJournal article

  41. Published

    A robust force field based method for calculating conformational energies of charged drug-like molecules. / Pøhlsgaard, Jacob; Harpsøe, Kasper; Jørgensen, Flemming Steen; Olsen, Lars.

    In: Journal of Chemical Information and Modeling, Vol. 52, No. 2, 2012, p. 409-419.

    Publication: Research - peer-reviewJournal article

  42. Published

    Absorption difference between diacylglycerol oil and butter blend containing deacylglycerol oil. / Kristensen, Janni Brogaard; Jørgensen, Henry; Mu, Huiling.

    In: European Journal of Lipid Science and Technology, Vol. 114, No. 2, 2012, p. 146-152.

    Publication: Research - peer-reviewJournal article

  43. Published

    An electrochemical approach to protein adsorption at charged interfaces. / Hartvig, Rune Andersen.

    København : Det Farmaceutiske Fakultet, 2012. 127 p.

    Publication: ResearchPh.D. thesis

  44. Published

    Assessing element-specific patterns of bioaccumulation across New England lakes. / Ward, Darren M.; Mayes, Brandon; Stürup, Stefan; Folt, Carol L.; Chen, Celia Y.

    In: Science of the Total Environment, Vol. 421-422, No. 3-4, 2012, p. 230-237.

    Publication: Research - peer-reviewJournal article

  45. Published

    Behaviour of HPMC compacts investigated using UV-imaging. / Pekka Pajander, Jari; Baldursdottir, Stefania G.; Rantanen, Jukka; Østergaard, Jesper.

    In: International Journal of Pharmaceutics, Vol. 427, No. 2, 2012, p. 345-353.

    Publication: Research - peer-reviewJournal article

  46. Published
  47. Published

    Comparison of polymeric siRNA nanocarriers in murine LPS-activated macrophage cell line: Gene silencing, toxicity and off-target gene expression. / Jensen, Linda Boye; Griger, Joscha; Naeye, Broes; Varkouhi, Amir K. ; Raemdonck, Koen; Schiffelers, Raymond; Lammers, Twan; Storm, Gert; Smedt, Stefaan C. de; Sproat, Brian S.; Nielsen, Hanne Mørck; Foged, Camilla.

    In: Pharmaceutical Research, Vol. 29, 2012, p. 669-682.

    Publication: Research - peer-reviewJournal article

  48. Published

    Correlation between enzyme activity an stability of a protease, an alpha-amaylase and a lipase in a simplified liquid laundry detergent system, determined by differential scanning calorimetry. / Lund, Henrik; Kaasgaard, Svend Gunnar; Skagerlind, Peter ; Jørgensen, Lene; Jørgensen, Christian Isak; van de Weert, Marco.

    In: Journal of Surfactants and Detergents, Vol. 15, 2012, p. 9-21.

    Publication: Research - peer-reviewJournal article

  49. Published

    Cyclodextrins : efficient biocompatible solubilizing excipients for bromhexine liquid and semi-solid drug delivery systems. / Stojanov, Mladen; Nielsen, Hanne Mørck; Larsen, Kim Lambertsen.

    In: International Journal of Pharmaceutics, Vol. 422, No. 1-2, 2012, p. 349-355.

    Publication: Research - peer-reviewJournal article

  50. Published

    Delivery of dermatan sulfate from polyelectrolyte complex-containing alginate composite microspheres for tissue regeneration. / Wen, Yanhong; Grøndahl, Lisbeth; Gallego, Monica R.; Jørgensen, Lene; Møller, Eva Horn; Nielsen, Hanne Mørck.

    In: Biomacromolecules, Vol. 13, 2012, p. 905-917.

    Publication: Research - peer-reviewJournal article

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